HCID 54462082, compound → HCID 13391719, compound

Participants

Reaction Steps

A solution of 2.0 g of the compound obtained in Example 38 in 20 ml of ethanol was stirred in a hydrogen atmosphere at atmospheric pressure and room temperature in the presence of 100 mg of 10% palladium-on-charcoal for an hour. The solution was filtered and concentrated to dryness in vacuo. The residue was subjected to silica gel column chromatography, eluted with dichloromethane to give 1.6 g (62%) of the desired compound as colorless needles, mp 41°-42° C.

Provenance & Evidence