Nitric Acid → HCID 86740693, compound

Participants

Reaction Steps

To a solution of 10 ml conc. sulfuric acid stirred at 0° C. was added 2-cyano-thiophene (4.0 g, 0.036 mole). Six mililiters of a mixture of 1:1 conc. sulfuric acid and fuming nitric acid was added dropwise to the solution and the temperature was maintained between 10° C. and 15° C. The reaction mixture was allowed to warm-up to room temperature after addition was completed and was stirred for an additional hour. The dark red solution was quenched with 50 ml of ice water and stirred vigorously. A yellow solid precipitated out. The solid was collected on a filter and washed with ice water (2×5 ml). This solid weighed 3.7 g (66%) and is a mixture of 4- & 5-nitro 2-cyano thiophene with 1:2 ratio.

Provenance & Evidence