反应详情

34 Grams of 3-formylcarbostyril was suspended in 800 ml of methanol, and 7.4 g of sodium borohydride was added gradually thereto under ice-cooled condition with stirring. The reaction mixture was further stirred under ice-cooling for 3 hours. The precipitated crystals were collected by filtration and recrystallized from methanol to obtain 33.2 g of 3-hydroxymethylcarbostyril in the form of colorless prism-like crystals.

1. temperatureunder ice-cooled condition
2. stirringThe reaction mixture was further stirred under ice-
3. temperaturecooling for 3 hours
4. filtrationThe precipitated crystals were collected by filtration
5. customrecrystallized from methanol