HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-fluorobenzaldehyde → HCID 70040617, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-fluorobenzaldehyde | HCID 67847 | — |
| Reactant | Methyl 3-aminocrotonate | HCID 643918 | — |
| Reactant | 3-(N-benzyl-N-methylamino)-2,2-dimethylpropyl acetoacetate | HCID 10108340 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 70040617 | HCID 70040617 | 6.3% |
Reaction Steps
A mixture of 170 mg of 2-chloro-6-fluorobenzaldehyde, 137 mg of methyl 3-aminocrotonate and 345 mg of 3-(N-benzyl-N-methylamino)-2,2-dimethylpropyl acetoacetate in 2 ml of 2-propanol was reacted and then purified in the same way as in Example 8 to yield 36 mg of the desired compound (168).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04578395 |
| Source dataset | uspto-grants-1986_03 |
| ORD ID | ord-b1d584c1126e423abe1fc36d6c8299c5 |
| Source note | uspto-grants-1986_03 |