[4S]-1-[(Phenylmethoxy)carbonyl]-4-(1-piperidinyl)-L-proline, methyl ester → [4S]-4-(1-Piperidinyl)-L-proline, methyl ester

Beteiligte Stoffe

Reaktionsschritte

A solution of 10.0 g of [4S]-1-[(phenylmethoxy)carbonyl]-4-(1-piperidinyl)-L-proline, methyl ester in 100 ml of methanol is treated with a suspension of 2 g of 5% palladium on charcoal in 10 ml of water and placed under 3 atmospheres of hydrogen. After an equivalent quantity of hydrogen is consumed, the suspension is filtered and the solvent evaporated to give the title compound.

Herkunft & Nachweise