反应详情

A mixture of chromone-3-carboxylic acid (1.25 g) and thionyl chloride (6 ml) was heated at reflux for 5 minutes. The reaction mixture was then diluted with cyclohexane (15 ml) and ice-cooled. The crystalline precipitate was collected by filtration, washed with cyclohexane and dried under vacuum to give chromone-3-carbonyl chloride (1.2 g).

1. temperaturewas heated
2. temperatureat reflux for 5 minutes
3. temperaturecooled
4. filtrationThe crystalline precipitate was collected by filtration
5. washwashed with cyclohexane
6. customdried under vacuum