Ammonia → 7-Methoxy-1-naphthaleneethanamine

HRID 483394Notes

Reaction equation

HRID 483394 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]#[N:15])=[CH:5][CH:4]=1.N.[H][H]>C(O)C.[Ni]>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][CH2:14][NH2:15])=[CH:5][CH:4]=1

Participants

6

Reactant 3

HCID 222AmmoniaHCID 112640682-(7-Methoxynaphthalen-1-yl)acetonitrileHCID 178418361HCID 178418361, compound

Product 1

HCID 110526677-Methoxy-1-naphthaleneethanamine

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

A solution of (7-methoxynaphth-1-yl)acetonitrile in ethanol saturated with ammonia is placed in an autoclave. Raney nickel and hydrogen at 300 atmospheres are added.

Sources & evidence

ORD record
ord-c0ff9b40b3094a0f82be5a686d06e066
Source dataset
uspto-grants-1993_07
Patent number
US05225442

Reaction notes

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