Hydrochloric Acid → HCID 19752401, compound

Participants

Reaction Steps

A suspension of 50 q of the hydrochloride salt from Step 1, 500 mL water, 250 mL ether and 170 mL of 1 N hydrochloric acid was treated with a solution of 12.3 q sodium nitrite in 50 mL of water. After stirring for 2 h at room temperature the reaction mixture was extracted twice with ether. The combined extracts were washed with water and dried over MgSO4. Filtration and concentration gave N-nitroso-N-(p-chlorobenzyl)-4-t-butylaniline.

Provenance & Evidence