HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 15035367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 15035366 | HCID 15035366 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Sodium chloride; water | HCID 57417360 | — |
| Product | HCID 15035367 | HCID 15035367 | — |
Reaction Steps
To 200 mg of 1-(p-chlorobenzyl)-5-fluoro-3-methylthioindole-2-acetic acid from Example 4 in a mixture of 3 mL water and 3 mL ethanol was added 1.6 q of oxone. After stirring for 6 h the reaction mixture was diluted with brine and ether. The ether layer was washed with 1 N HCl, and brine and dried over MgSO4. Filtration and concentration gave the title compound, mp 202°-202.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05225421 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-b5024d0c5d3f466c95cbac223e03ed32 |
| Source note | uspto-grants-1993_07 |