Fluorene → HCID 129845837, compound

Participants

Reaction Steps

To 200 ml of THF and 16.5 g of fluorene cooled to a temperature of -50° C. or lower in a 500-ml flask thoroughly purged with nitrogen was added 67 ml of a dil. methyllithium diethyl ether solution (1.4 M) dropwise over 30 minutes. The mixture was warmed gradually to room temperature and subjected to reaction for 3 hours. The reaction mixture was cooled back to a temperature of -50° C. or lower and 10 g of 6,6-dimethylfulvene was added dropwise over 30 minutes. After the addition was completed, the solution was warmed slowly to room temperature and subjected to reaction for 2 days. The reaction was terminated by the addition of 60 ml of H2O, and the ether layer was separated and dehydrated over anhydrous MgSO4. Drying ether by evaporation, gave 17.6 g of 2-cyclopentadienyl-2-fluorenylpropane as crude crystals.

Provenance & Evidence