反应详情

To a solution of 1-(4-carboxyphenyl)-3,4-dihydrocarbostyril (0.2 g) in chloroform (5 ml) is added thionyl chloride (0.8 ml) and the mixture is refluxed with heating for 1 hour. Then, chloroform and thionyl chloride are distilled off under reduced pressure to give 4-(3,4-dihydrocarbostyril-1-yl)benzoic acid chloride.

1. temperaturethe mixture is refluxed
2. temperaturewith heating for 1 hour
3. distillationThen, chloroform and thionyl chloride are distilled off under reduced pressure