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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 483588Generated: October 30, 2026

Imidazo(1,2-a)pyridine → HCID 19925050, compound

https://huagongshe.com/reaction/483588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazo(1,2-a)pyridineHCID 78960—
ReactantN-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamideHCID 10052253—
SolventAcetonitrileHCID 6342—
ProductHCID 19925050HCID 1992505081.4%

Reaction Steps

A mixture of 1.5 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 1.03 g of imidazo[1,2-a]pyridine in 25 ml of acetonitrile is refluxed under argon for 3.5 hours. The solvent is evaporated and the residue stirred with ether and collected by centrifugation. The solid is washed several times with ether and vacuum dried to give 1.5 g of the desired product as a white powder, m.p. 133°-135° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05225425
Source datasetuspto-grants-1993_07
ORD IDord-8a23fea0c5a7436a97916a1d9a91467e
Source noteuspto-grants-1993_07