3-(Dimethylamino)-1-phenyl-1-propanone → 3-(Dimethylamino)-1-phenylpropan-1-ol

HRID 483667Notes

Reaction equation

HRID 483667 reaction equation
[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][C:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:6].B#B>>[CH3:13][N:2]([CH3:1])[CH2:3][CH2:4][CH:5]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[OH:6]

Participants

3

Reactant 2

HCID 770423-(Dimethylamino)-1-phenyl-1-propanone2×HCID 6328200Diboron

Product 1

HCID 1106653-(Dimethylamino)-1-phenylpropan-1-ol

Procedure

In that process 3-dimethylamino propiophenone (formula II) is liberated from its hydrochloride salt and reduced with diborane to yield 3-dimethylamino-1-phenyl-1-propanol (formula III) ##STR2##

Sources & evidence

ORD record
ord-5fd0d3af3e5444dab1ef8fad16400cc4
Source dataset
uspto-grants-1993_07
Patent number
US05225585

Reaction notes

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