HCID 15157722, compound → HCID 9795071, compound

HRID 483779Notes

Reaction equation

HRID 483779 reaction equation
[N:1]12[CH2:8][CH2:7][CH:4]([CH2:5][CH2:6]1)[CH:3]([C:9]1[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=3)[NH:11][C:10]=1C(O)=O)[CH2:2]2>CN(C)C1C=CC=CC=1>[CH3:19][O:18][C:15]1[CH:16]=[C:17]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[CH:3]1[CH:4]2[CH2:5][CH2:6][N:1]([CH2:8][CH2:7]2)[CH2:2]1

Participants

3

Reactant 1

HCID 15157722HCID 15157722, compound

Product 1

HCID 9795071HCID 9795071, compound

Reagents, catalysts & solvents 1

HCID 949N,N-DimethylanilineSolvent

Procedure

100 mg of 3-(3-quinuclidinyl)-5-methoxyindole-2-carboxylic acid are stirred at 180° in N,N-dimethylaniline for 8 hours. The mixture is then worked up as is customary. 3-(5-methoxy-3-indolyl)quinuclidine is obtained.

Sources & evidence

ORD record
ord-1ca501ebb996437d8cc334444609e59f
Source dataset
uspto-grants-1993_07
Patent number
US05227386

Reaction notes

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