化工社化工社 化学情報印刷レポート · 研究参考用
Arecoline → 3-Methoxycarbonyl-1-methyl-4-(3-trifluoromethylphenyl)piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Arecoline | HCID 2230 | — |
| 反応物 | Benzene, 1-bromo-3-(trifluoromethyl)- | HCID 9817 | — |
| 生成物 | 3-Methoxycarbonyl-1-methyl-4-(3-trifluoromethylphenyl)piperidine | HCID 19751261 | — |
反応手順
3-methoxycarbonyl-1-methyl-4-(3-trifluoromethylphenyl)piperidine was prepared as the cis/trans mixture from arecoline and 3-bromo-trifluoromethylbenzene as described (J. Org. Chem. 22 (1957) 261). The product was purified by vacuum distillation. B.p. 90°-110° C./0.7 mmHg.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05227379 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-1a232e0c4acd4c8195c3f74b996ba32d |
| 出典メモ | uspto-grants-1993_07 |