Methanesulfonyl chloride → [(Methylethyl)sulfonyl][2-(4-{2-[(methylsulfonyl)amino]ethyl}phenyl)propyl]amine

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Reaction Steps

Scheme Va, step C: {2-[4-(2-Aminoethyl)phenyl]propyl}[(methylethyl)sulfonyl]amine (0.15 g, 0.53 mmol), methanesulfonyl chloride (0.1 mL, 0.58 mmol) and DBU (0.1 mL, 0.61 mmol) were combined and sulfonylation was carried out in a manner analogous to the procedure described in example 2 to provide the final title compound, [(methylethyl)sulfonyl][2-(4-{2-[(methylsulfonyl)amino]ethyl}phenyl)propyl]amine, (0.15 g, 78%) as a white crystalline solid. Electron spray M.S. 363 (M*+H). Analysis for C15H26N2O4S2:

Provenance & Evidence