Tributyltin Chloride → HCID 19751730, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1-3 (6.97 g, 17.5 mmoles) in THF (150 ml) was cooled to -75° C. and treated with n-butyl lithium (n-BuLi)(17.5 mmoles) dropwise. After stirring at -70° C. for 1 hr, tributyltin chloride (5.70 g, 17.5 mmol) was added dropwise. This was stirred at -70° C. for 2 hours and then overnight as the temperature was allowed to rise to ambient temperature. The solvent was subsequently removed and the residue was taken up in ether (500 ml), washed with H2O and brine, and dried with Na2SO4. Solvent removal gave 1-4 as a viscous oil.

Provenance & Evidence