(Phenylmethoxy)-n-[2-(5-{2-[(phenylmethoxy)carbonylamino]ethyl}(2-thienyl))ethyl]carboxamide → 2-[5-(2-Aminoethyl)-2-thienyl]ethylamine

Participants

Reaction Steps

(Phenylmethoxy)N-[2-(5-{2-[(phenylmethoxy)carbonylamino]ethyl}(2-thienyl))ethyl]carboxamide (1.6 g, 3.6 mmol) and 10% palladium on carbon (1.0 g, 62 mole %) were combined and hydrogenation was carried out in a manner analogous to the procedure described in example 6 to provide the intermediate title compound, 2-[5-(2-aminoethyl)-2-thienyl]ethylamine, (0.935 g, 55%) as a colorless oil.

Provenance & Evidence