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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 483915Generated: October 25, 2026

Perfluoropropionyl fluoride → 1,1,1,3,3,4,4,4-Octafluoro-2-(trifluoromethyl)-2-butanol

https://huagongshe.com/reaction/483915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPerfluoropropionyl fluorideHCID 67912—
ReactantPotassium FluorideHCID 522689—
SolventAcetonitrileHCID 6342—
Product1,1,1,3,3,4,4,4-Octafluoro-2-(trifluoromethyl)-2-butanolHCID 160813—

Reaction Conditions

Temperature-196 °C

Reaction Steps

By operating as in the above examples, 0.26 g of KF (4.5 mmol) was charged to the reactor, and then 4.0 ml of anhydrous acetonitrile was injected through the pierceable cap; the whole was then cooled down to -196° C. with the residual air being evacuated; then, 2.0 mmol of pentafluoropropionyl fluoride

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05227539
Source datasetuspto-grants-1993_07
ORD IDord-26b6efaca80344a497d3f837a6d8c214
Source noteuspto-grants-1993_07