HCID 20633661, compound → 2-[6-(2-Aminoethyl)-3-pyridyl]ethylamine

HRID 48392Notes

Reaction equation

HRID 48392 reaction equation
C1(COC([NH:11][CH2:12][CH2:13][C:14]2[CH:15]=[N:16][C:17]([CH2:20][CH2:21][NH:22]C(OCC3C=CC=CC=3)=O)=[CH:18][CH:19]=2)=O)C=CC=CC=1>[Pd]>[NH2:22][CH2:21][CH2:20][C:17]1[N:16]=[CH:15][C:14]([CH2:13][CH2:12][NH2:11])=[CH:19][CH:18]=1

Participants

3

Reactant 1

HCID 20633661HCID 20633661, compound

Product 1

HCID 227432312-[6-(2-Aminoethyl)-3-pyridyl]ethylamineYield 55%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

(Phenylmethoxy)-N-[2-(6-{2-[(phenylmethoxy)carbonylamino]ethyl}(3-pyridyl))ethyl]carboxamide (3.6 mmol) and 10% palladium on carbon (1.0 g, 62 mole %) were combined and hydrogenation was carried out in a manner analogous to the procedure described in example 6 to provide the intermediate title compound, 2-[6-(2-aminoethyl)-3-pyridyl]ethylamine, (55%) as a colorless oil.

Sources & evidence

ORD record
ord-f0f6aa7c24c34da189c66a36d63c10cd
Source dataset
uspto-grants-2004_03
Patent number
US06703425B2

Reaction notes

Loading…