HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67881371, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 57275675 | HCID 57275675 | — |
| Solvent | Diethyl ether ethanol | HCID 21585056 | — |
| Product | HCID 67881371 | HCID 67881371 | — |
Reaction Steps
(8aR,12aS,13aS)-3-methoxy-12-(3-chloropropanesulfonyl)-5,6,8a,9,10,11,12,12a,13,13a-decahydro-8H-isoquino[2,1-g][1,6]naphthyridine as an oil, which was converted to the hydrochloride salt in ethanol/ether mixture by treatment with anhydrous hydrochloric acid, to give (8aR,12aS,13aS)-3-methoxy-12-(3-chloropropanesulfonyl)-5,6,8a,9,10,11,12,12a,13,13a-decahydro-8H-isoquino[2,1-g][1,6]naphthyridine hydrochloride, m.p. 203°-205° C., [α]D25 =+28.7° (c=0.55, CH3OH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05229387 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-c1d293a4fcd64394a6f049b75fafe012 |
| Source note | uspto-grants-1993_07 |