HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropane → 1-(1-Methylethyl)-6-(methylthio)-benz[cd]indol-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 6-(Methylthio)benz[cd]indol-2(1H)-one | HCID 19750824 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(1-Methylethyl)-6-(methylthio)-benz[cd]indol-2(1H)-one | HCID 19750817 | — |
Reaction Steps
A mixture of 2.0 g of 6-(methylthio)-benz[cd]indol-2(1H)-one (Example 2), 0.48 g of 60% sodium hydride and 2.33 ml of 2-bromopropane in 100 ml of N,N-dimethylformamide is reacted for 23 hours using the conditions of Example 4 to yield 1.15 g of the desired product as a bright yellow solid, m.p. 70°-71° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05229411 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-d5950ed189b64f3ab3497dc8500e9eaf |
| Source note | uspto-grants-1993_07 |