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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48412Generated: October 29, 2026

2-Aminoindane → 4-(2-Indanylamino)-5-phenylthieno[2,3-d]pyrimidine

https://huagongshe.com/reaction/48412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminoindaneHCID 76310—
Reactant4-Chloro-5-phenylthieno[2,3-d]pyrimidineHCID 708730—
Product4-(2-Indanylamino)-5-phenylthieno[2,3-d]pyrimidineHCID 12094062100%

Reaction Steps

Using 4-chloro-5-phenylthieno[2,3-d]pyrimidine (50 mg, 0.20 mmol) and 2-aminoindan (110 mg, 0.80 mmol), a similar procedure to Production Example 190 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=2:1) to obtain the title compound (67 mg, 0.20 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703421B1
Source datasetuspto-grants-2004_03
ORD IDord-6c4d35318ce44ea7a901e26adae396ac
Source noteuspto-grants-2004_03