HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminoindane → 4-(2-Indanylamino)-5-phenylthieno[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminoindane | HCID 76310 | — |
| Reactant | 4-Chloro-5-phenylthieno[2,3-d]pyrimidine | HCID 708730 | — |
| Product | 4-(2-Indanylamino)-5-phenylthieno[2,3-d]pyrimidine | HCID 12094062 | 100% |
Reaction Steps
Using 4-chloro-5-phenylthieno[2,3-d]pyrimidine (50 mg, 0.20 mmol) and 2-aminoindan (110 mg, 0.80 mmol), a similar procedure to Production Example 190 was carried out. The product obtained was purified by silica gel chromatography (hexane:ethyl acetate=2:1) to obtain the title compound (67 mg, 0.20 mmol) having the following physical properties:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703421B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-6c4d35318ce44ea7a901e26adae396ac |
| Source note | uspto-grants-2004_03 |