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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 48418Generated: October 26, 2026

Formamide → HCID 178439799, compound

https://huagongshe.com/reaction/48418

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormamideHCID 713—
ReactantEthyl 2-amino-4-(1-methylethyl)-3-thiophenecarboxylateHCID 2756460—
ProductHCID 178439799HCID 178439799—

Reaction Steps

Using ethyl 2-amino-4-isopropylthiophene-3-carboxylate (800 mg, 3.8 mmol) and formamide (5 ml), a similar procedure to a) in Production Example 208 was carried out to obtain 4-hydroxy-5-isopropylthieno[2,3-d]pyrimidine (330 mg, 1.7 mmol) having the following physical properties:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06703421B1
Source datasetuspto-grants-2004_03
ORD IDord-5be357e69e144062af34fbcf8baee434
Source noteuspto-grants-2004_03