Boron tribromide → Methanone, cyclopentyl(4-hydroxyphenyl)-

HRID 484343Notes

Reaction equation

HRID 484343 reaction equation
[CH:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([O:14]C)=[CH:10][CH:9]=2)=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.B(Br)(Br)Br>ClCCl>[CH:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=2)=[O:7])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 251071Cyclopentyl(4-methoxyphenyl)methanone

Product 1

HCID 12239542Methanone, cyclopentyl(4-hydroxyphenyl)-

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound is prepared in analogy to the procedure of Example II from 30 g (0.147 mol) of the compound from Example VI and 290 ml of a 1M solution of boron tribromide (0.29 mmol) in dichloromethane.

Sources & evidence

ORD record
ord-195a6bee1ed246abbda67cbfd4451594
Source dataset
uspto-grants-1993_07
Patent number
US05231103

Reaction notes

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