HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl formate → N-[2-(3-Methoxyphenyl)ethyl]formamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | 3-Methoxyphenethylamine | HCID 74866 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-[2-(3-Methoxyphenyl)ethyl]formamide | HCID 13562936 | 99.9% |
Reaction Steps
A solution of 25 Kg of 3-methoxyphenethylamine, 9 Kg of toluene and 23 Kg of ethyl formate was heated to reflux (62°-76° C.) for 6 hours. The volatile components were removed under vacuum, the residue treated with a further 9 Kg of toluene and the solvent removed under vacuum, leaving 29.6 Kg of N-formyl-3-methoxy-phenethylamine as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05231181 |
| Source dataset | uspto-grants-1993_07 |
| ORD ID | ord-2171a0c67ac54bc58dfb0f1985e59042 |
| Source note | uspto-grants-1993_07 |