HCID 178449946, compound → HCID 178449950, compound

HRID 48452Notes

Reaction equation

HRID 48452 reaction equation
Cl.[C:2]([NH2:7])(=[O:6])[C:3]([CH3:5])=[CH2:4].[NH2:8][C@H:9]([C:17]([OH:19])=[O:18])[CH2:10][CH2:11][CH2:12][NH:13][C:14](=[NH:16])[NH2:15]>O>[C:2]([NH2:7])(=[O:6])[C:3]([CH3:5])=[CH2:4].[NH2:8][C@H:9]([C:17]([OH:19])=[O:18])[CH2:10][CH2:11][CH2:12][NH:13][C:14](=[NH:15])[NH2:16]

Participants

3

Reactant 1

HCID 178449946HCID 178449946, compound

Product 1

HCID 178449950HCID 178449950, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The obtained arginine-mono-methacrylamide hydrochloride(4.84 g) was dissolved in 40 ml of distilled water, and bubbled with nitrogen gas for 1 hour. Potassium persulfate(60 mg) was added to the solution, and dissolved in it. The reaction mixture was refluxed by heating for 3 hours, then cooled to room temperature, and poured into acetone, so that precipitates were deposited. The supernatant was discarded, and acetone was again added to the precipitates and obtained mixture was stirred. The deposition was collected by filtration and dried to obtain the target polymer (white powder, 3.05 g).

Workup

  1. custombubbled with nitrogen gas for 1 hour
  2. additionPotassium persulfate(60 mg) was added to the solution
  3. dissolutiondissolved in it
  4. temperatureThe reaction mixture was refluxed
  5. temperatureby heating for 3 hours
  6. additionpoured into acetone
  7. customso that precipitates
  8. additionacetone was again added to the
  9. customprecipitates
  10. customobtained mixture
  11. filtrationThe deposition was collected by filtration
  12. customdried
  13. customto obtain the target polymer (white powder, 3.05 g)

Sources & evidence

ORD record
ord-6efe0540645444a58e5093ab19d41145
Source dataset
uspto-grants-2004_03
Patent number
US06703468B1

Reaction notes

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