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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 484578Generated: November 3, 2026

Diethyl Ether → HCID 10008954, compound

https://huagongshe.com/reaction/484578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
Reactant5-MethylthiazoleHCID 137980—
ReactantN-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamideHCID 10052253—
SolventTolueneHCID 1140—
ProductHCID 10008954HCID 1000895488.6%

Reaction Steps

A mixture of 3.6 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 3.46 g of 5-methylthiazole in 25 ml of toluene is refluxed under inert gas for 1.5 hours, cooled and poured into 200 ml of ether. The organic layer is decanted and the solid washed with ether and collected to give 3.8 g of the desired product as a white solid, m.p. 173°-175° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05231182
Source datasetuspto-grants-1993_07
ORD IDord-0d3845c3926943e68ff3c949215f93b0
Source noteuspto-grants-1993_07