Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Propanesulfonyl chloride, 2-methyl- → 2-Methyl-propane-1-sulfonic acid 6-(2,4-diamino-pyrimidin-5-ylmethyl)-1-methyl-1H-indol-4-yl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Propanesulfonyl chloride, 2-methyl- | HCID 182236 | — |
| 반응물 | 6-(2,4-Diamino-pyrimidin-5-ylmethyl)-1-methyl-1H-indol-4-ol | HCID 22742890 | — |
| 생성물 | 2-Methyl-propane-1-sulfonic acid 6-(2,4-diamino-pyrimidin-5-ylmethyl)-1-methyl-1H-indol-4-yl ester | HCID 86588571 | — |
반응 단계
This compound was produced by reaction of 6-(2,4-diamino-pyrimidin-5-ylmethyl)-1-methyl-1H-indol-4-ol (Example 4,269 mg, 1.00 mmol) with 2-methylpropane-1-sulfonyl chloride (188 mg, 1.20 mmol), following the procedure detailed in Example 5c. Yield: 58 mg (15%). White solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06703397B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-61a43b6f644d4704a679f4c56d95a96d |
| 출처 메모 | uspto-grants-2004_03 |