HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Cyclohexadiene → (3S-trans)-3-[(2,6-Dimethoxybenzoyl)amino]-1-hydroxy-4-methyl-2-azetidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Cyclohexadiene | HCID 12343 | — |
| Reactant | (3S-trans)-3-[(2,6-dimethoxybenzoyl)amino]-4-methyl-1-[(phenylmethyl)oxy]-2-azetidinone | HCID 13036849 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (3S-trans)-3-[(2,6-Dimethoxybenzoyl)amino]-1-hydroxy-4-methyl-2-azetidinone | HCID 13036851 | — |
Reaction Steps
To a stirred solution of (3S-trans)-3-[(2,6-dimethoxybenzoyl)amino]-4-methyl-1-[(phenylmethyl)oxy]-2-azetidinone (0.848 g) in absolute ethanol (20 ml) under nitrogen is added 1,4-cyclohexadiene (8 ml) and freshly prepared palladium black (approximately 0.85 g). After one hour the reaction mixture is filtered and evaporated to a solid (0.605 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04533660 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-f11ae1338b2c42aaab4c9629d7f790f8 |
| Source note | uspto-grants-1985_08 |