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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 484695Generated: October 27, 2026

2-Amino-6-Chloropyrazine → N-(6-chloro-pyrazin-2-yl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

https://huagongshe.com/reaction/484695

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-ChloropyrazineHCID 118458—
Reactantpropyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxideHCID 54703136—
ProductN-(6-chloro-pyrazin-2-yl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxideHCID 54703135—

Reaction Steps

This compound was prepared from propyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide and 2-amino-6-chloro-pyrazine analogous to Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04533664
Source datasetuspto-grants-1985_08
ORD IDord-348d5de478e64e698bf312a345400272
Source noteuspto-grants-1985_08