HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylboronic acid → 5-(4-Fluorophenyl)pyridin-3-ylmethyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | HCID 22743455 | HCID 22743455 | — |
| Product | 5-(4-Fluorophenyl)pyridin-3-ylmethyl acetate | HCID 22743454 | — |
Reaction Steps
5-Bromo-3-acetoxymethylpyridine is reacted with 4-fluorobenzeneboronic acid as described in Example 1. The 5-(4-fluorophenyl)pyridin-3-ylmethyl acetate obtained is saponified by conventional methods and subsequently oxidized to give 5-(4-fluorophenyl)nicotinic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703509B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-de928753122c4e818d80a8c0b2b7509f |
| Source note | uspto-grants-2004_03 |