HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 2-[(2-Methyl-4-aminophenyl)amino]-1-pyrroline, dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | N-(2-Methyl-4-nitrophenyl)-3,4-dihydro-2H-pyrrol-5-amine | HCID 13520142 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-[(2-Methyl-4-aminophenyl)amino]-1-pyrroline, dihydrochloride | HCID 131714294 | — |
Reaktionsschritte
The product compound of Example 8 was dissolved in 1.2 liter of ethanol containing 53.4 ml of concentrated hydrochloric acid and hydrogenated at 2 psi over 5% palladium on carbon. After removal of catalyst by filtration, the filtrate was concentrated in vacuo to give 85 g of the title compound. Structure assignment was supported by the nmr spectrum and by elemental analysis.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04533739 |
| Quelldatensatz | uspto-grants-1985_08 |
| ORD ID | ord-7b907801ad1e442e9344b86ae0bea55e |
| Quellennotiz | uspto-grants-1985_08 |