Butyryl chloride → 2-[(2-Methyl-4-(butanamido)phenyl)amino]-1-pyrroline, hydrochloride

HRID 484795Notes

Reaction equation

HRID 484795 reaction equation
[C:1]([Cl:6])(=[O:5])[CH2:2][CH2:3][CH3:4].Cl.Cl.[CH3:9][C:10]1[CH:15]=[C:14]([NH2:16])[CH:13]=[CH:12][C:11]=1[NH:17][C:18]1[CH2:22][CH2:21][CH2:20][N:19]=1>>[ClH:6].[CH3:9][C:10]1[CH:15]=[C:14]([NH:16][C:1](=[O:5])[CH2:2][CH2:3][CH3:4])[CH:13]=[CH:12][C:11]=1[NH:17][C:18]1[CH2:22][CH2:21][CH2:20][N:19]=1

Participants

3

Reactant 2

HCID 8855Butyryl chlorideHCID 1317142942-[(2-Methyl-4-aminophenyl)amino]-1-pyrroline, dihydrochloride

Product 1

HCID 1317142962-[(2-Methyl-4-(butanamido)phenyl)amino]-1-pyrroline, hydrochloride

Procedure

The title compound was prepared by the method of Example 21 using 30.5 mmole of butanoyl chloride and 1.0 g (3.8 mmole) of the product compound of Example 9. Structure assignment was supported by the nmr spectrum and by elemental analysis.

Sources & evidence

ORD record
ord-3fcef290bd9e44f3ad84d376408c30b1
Source dataset
uspto-grants-1985_08
Patent number
US04533739

Reaction notes

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