Ethyl chloroformate → 2-[(2-Methyl-4-(ethoxycarbonylamino)phenyl)-amino]-1-pyrroline, hydrochloride

Participants

Reaction Steps

The title compound was prepared by the method of Example 21 using 30.5 mmole of ethyl chloroformate and 1.0 g (3.8 mmole) of the product compound of Example 9. Complete reaction, as indicated by thin-layer chromatography (See Example 21), required heating for a second day with an additional 30.5 mmole of ethyl chloroformate. Structure assignment was supported by the nmr spectrum and by elemental analysis.

Provenance & Evidence