Acetic Anhydride → 2-[(2-Methyl-3-acetamidophenyl)amino]-1-pyrroline, hydrochloride

HRID 484808Notes

Reaction equation

C(O[C:5](=[O:7])[CH3:6])(=O)C.[ClH:8].Cl.[CH3:10][C:11]1[C:16]([NH2:17])=[CH:15][CH:14]=[CH:13][C:12]=1[NH:18][C:19]1[CH2:23][CH2:22][CH2:21][N:20]=1>>[ClH:8].[CH3:10][C:11]1[C:16]([NH:17][C:5](=[O:7])[CH3:6])=[CH:15][CH:14]=[CH:13][C:12]=1[NH:18][C:19]1[CH2:23][CH2:22][CH2:21][N:20]=1

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 699300682-[(2-Methyl-3-aminophenyl)amino]-1-pyrroline, dihydrochloride

Product 1

HCID 179160262-[(2-Methyl-3-acetamidophenyl)amino]-1-pyrroline, hydrochloride

Procedure

The title compound (2.5 g) was prepared by the method of Example 17 using acetic anhydride and 3.0 g of the product aniline of Example 45. Structure assignment was supported by the nmr spectrum and by elemental analysis.

Sources & evidence

ORD record: ord-356d670894bd45ab858baac9cef0249c
Source dataset: uspto-grants-1985_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04533739

Reaction notes

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