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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 484882Generated: October 27, 2026

3-Amino-4-chloroindazole → 1-(3-Dimethylaminobutyl)-3-amino-5-chloroindazole

https://huagongshe.com/reaction/484882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-chloroindazoleHCID 313444—
Reactant(3-Bromopropyl)diethylamine hydrobromideHCID 12639158—
Reactant1-(3-Diethylaminopropyl)-3-amino-4-chloroindazoleHCID 13229325—
Reactant3-Amino-5-chloro-1h-indazoleHCID 21516164—
Product1-(3-Dimethylaminobutyl)-3-amino-5-chloroindazoleHCID 20135798—

Reaction Steps

The same procedures for preparing 1-(3-diethylaminopropyl)-3-amino-4-chloroindazole as described in Example 89 were repeated except that 1-(1-methyl-3-bromopropyl)-dimethylamine hydrobromide and 3-amino-5-chloroindazole were employed instead of the 3-bromopropyldiethylamine hydrobromide and the 3-amino-4-chloroindazole, respectively. As a result, 1-(3-dimethylaminobutyl)-3-amino-5-chloroindazole was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04533731
Source datasetuspto-grants-1985_08
ORD IDord-6b8e1726fc3641cdba2704f3f65d5323
Source noteuspto-grants-1985_08