HCID 86740227, compound → HCID 86740226, compound

HRID 484927Notes

Reaction equation

HRID 484927 reaction equation
[N:1]#[N:2].C(O[C:11]([N:13](C)[C@@H:14]([C:16]([NH:18][CH2:19][CH2:20][CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:17])[CH3:15])=O)C1C=CC=CC=1>C(O)C.[Pd]>[N:1]#[N:2].[CH3:11][NH:13][C@@H:14]([C:16]([NH:18][CH2:19][CH2:20][CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:17])[CH3:15]

Participants

4

Reactant 1

HCID 86740227HCID 86740227, compound

Product 1

HCID 86740226HCID 86740226, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of N2 -benzyloxycarbonyl-N2 -methyl-N-(3-phenylpropyl)-D-alaninamide (7.54 g.) in ethanol (200 ml.) containing palladium on carbon (10%, 200 mg.) was hydrogenated under pressure (40 p.s.i.g.), filtered and stripped of volatiles, affording N2 -methyl-N-(3-phenylpropyl)-D-alaninamide.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-ed90c5545b4f42aaa172f652043cd145
Source dataset
uspto-grants-1985_08
Patent number
US04533655

Reaction notes

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