反应详情

5.1 g of 2-chloro-4,6-bis[N-(2,2,6,6-tetramethyl-4-piperidyl)amino]-1,3,5-triazine [prepared as described in Preparation 9(b)] were reacted with 0.7 g of 1,8-diamino-4-aminomethyloctane, following the procedure described in Example 9. After completion of the reaction, the reaction mixture was poured into water and extracted with chloroform. The extract was dried over anhydrous potassium carbonate, and the solvent was distilled off. The residue was purified by column chromatography through silica gel, eluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine, to give the desired Compound No. 1 in the form of crystals melting at 148°-158° C.

1. customAfter completion of the reaction
2. extractionextracted with chloroform
3. dry with materialThe extract was dried over anhydrous potassium carbonate
4. distillationthe solvent was distilled off
5. customThe residue was purified by column chromatography through silica gel
6. washeluted with a 8:2:1 by volume mixture of ethyl acetate, ethanol and triethylamine