HCID 54058645, compound → HCID 54269061, compound

Participants

Reaction Steps

A solution of 1.57 g of 1D in 150 ml of methanol containing 0.40 g of palladium-on-carbon catalyst was hydrogenated (50 p.s.i.) in a Parr shaker overnight. The mixture was filtered and the methanol was evaporated from the filtrate under reduced pressure. The residue was dissolved in 100 ml of water, the solution was washed with ethyl acetate, the water was evaporated under reduced pressure, and the residue was subjected to very low pressure (<1 Torr.) and then recrystallized from methanol/ether to give 1, as a colorless solid, m.p.: 192°-193° C.

Provenance & Evidence