HCID 86740241, compound → HCID 86740240, compound
Reaction equation
CC(C)(OC([NH:7][C@H:8]1[C@H:11]([CH3:12])[N:10]([C:13](=[O:19])[CH2:14][C:15]([O:17][CH3:18])=[O:16])[C:9]1=[O:20])=O)C>ClCCl.FC(F)(F)C(O)=O>[NH2:7][C@H:8]1[C@H:11]([CH3:12])[N:10]([C:13](=[O:19])[CH2:14][C:15]([O:17][CH3:18])=[O:16])[C:9]1=[O:20]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- -10 °C
Procedure
(3S-trans)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-methyl-β,2-dioxo-1-azetidinepropionic acid, methyl ester (0.3 g) was dissolved in 10 ml of dichloromethane/trifluoroacetic acid (7:3) and stirred for 15 minutes at -10° C. After evaporation and treatment with ether, 0.31 g of the title compound was obtained as a crystalline material, melting point 75° C. dec.
Workup
- customAfter evaporation and treatment with ether
Sources & evidence
- ORD record
- ord-f41aeddbe5e14e06b833402fc11e34de
- Source dataset
- uspto-grants-1985_08
- Patent number
- US04534896
Reaction notes
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