反应详情

2-Bromo-4-methylpentanoyl chloride (IV, Example 2) is added dropwise to methyl alcohol (200 ml.) at 0°. After two hours the methanol is removed under reduce pressure and the residual oil is partitioned between chloroform and water. The chloroform is separated from the water and removed under reduced pressure to give a residual oil which is distilled under reduced pressure to give the title compound, b.p. 78°-90°/30 mm.

1. customAfter two hours the methanol is removed
2. customthe residual oil is partitioned between chloroform and water
3. customThe chloroform is separated from the water
4. customremoved under reduced pressure
5. customto give a residual oil which
6. distillationis distilled under reduced pressure