HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 485087Generated: October 30, 2026
Potassium Acetate → p-Methoxyphenylpropionic acid
https://huagongshe.com/reaction/485087
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | 1-(2-Bromo-1,1-dimethoxypropyl)-4-methoxybenzene | HCID 15579882 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | p-Methoxyphenylpropionic acid | HCID 257576 | 89% |
Reaction Steps
A mixture of 2-bromo-1,1-dimethoxy-1-(4'-methoxyphenyl)-propane (2.89 g; 0.01 mol), potassium acetate (1.2 g; 0.012 mol) and n-butanol (40 ml) is heated to 115° C. for 32 hours. By following the procedure of Example 1a, there is obtained the title product (1.60 g; 0.0089 mol). Yield, 89%; m.p. 56°-57° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04535166 |
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| Source dataset | uspto-grants-1985_08 |
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| ORD ID | ord-989820ee8f10408cbff27fcc1612efd8 |
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| Source note | uspto-grants-1985_08 |
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