HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → HCID 13253359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13253359 | HCID 13253359 | 70.6% |
Reaction Steps
2-Amino-4,5-dimethylthiazole (2.56 g., 20 mmoles), diethyl ethoxymethylenemalonate (4.8 g., 22 mmoles) and ethanol (5 ml.) were refluxed for 1 hour. The reaction mixture was cooled and the crude product precipitated with hexane. Purified 2-(2,2-dicarbethoxyethenylamino)-4,5-dimethylthiazole (4.21 g., m.p. 82°-83.5° C.) was obtained by recrystallization from hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04535081 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-c1da765cf8be4a4facca4385f6809beb |
| Source note | uspto-grants-1985_08 |