HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Didesmethylvenlafaxine → N-Desmethylvenlafaxine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Didesmethylvenlafaxine | HCID 9795857 | — |
| Reactant | 1-[alpha-(Aminomethyl)benzyl]cyclohexanol | HCID 13520304 | — |
| Reactant | Cyclohexanol hydrochloride | HCID 18413310 | — |
| Product | N-Desmethylvenlafaxine | HCID 3501942 | — |
Reaction Steps
By replacing 1-[α-(aminomethyl)benzyl]cyclohexanol with a molar equivalent amount of 1-[2-amino-1-(p-methoxyphenyl)ethyl]cyclohexanol in Example 7, 1-[1-(4-methoxyphenyl)-2-methylamino)ethyl]cyclohexanol hydrochloride (m.p. 164°-166° C.) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04535186 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-ea5042d20f764556b5ebb20ccf1f0dd1 |
| Source note | uspto-grants-1985_08 |