Ethylamine → HCID 20269767, compound

HRID 485213Notes

Reaction equation

HRID 485213 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][C:3]=1[O:4][CH:5]([CH3:11])[C:6]([O:8]CC)=O.[CH2:19]([NH2:21])[CH3:20]>C(O)C>[CH2:19]([NH:21][C:6](=[O:8])[CH:5]([O:4][C:3]1[CH:12]=[C:13]([N+:16]([O-:18])=[O:17])[CH:14]=[CH:15][C:2]=1[Cl:1])[CH3:11])[CH3:20]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 20269773HCID 20269773, compound

Product 1

HCID 20269767HCID 20269767, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2.74 g. of ethyl α-(2-chloro-5-nitrophenoxy)propionate, 0.77 g. of 70% aqueous solution of ethylamine and 15 ml. of ethanol was kept at room temperature for one night. The precipitate was separated by a filtration and recrystallized from a mixture of benzene-cyclohexane to obtain 2.5 g. of the object compound (melting point of 148° to 149° C.).

Workup

  1. additionA mixture of 2.74 g
  2. customThe precipitate was separated by a filtration
  3. customrecrystallized from a mixture of benzene-cyclohexane
  4. customto obtain 2.5 g

Sources & evidence

ORD record
ord-5a0751165b7d440f8055dffd1a78e5e7
Source dataset
uspto-grants-1985_08
Patent number
US04536209

Reaction notes

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