Sulfuric Acid → HCID 20270166, compound

HRID 485306Notes

Reaction equation

HRID 485306 reaction equation
C(O)(=O)C.[C:5]1([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1.[S:27](=[O:31])(=[O:30])([OH:29])[OH:28]>O>[S:27](=[O:29])(=[O:28])([OH:31])[OH:30].[C:5]1([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 70487236HCID 70487236, compound

Product 1

HCID 20270166HCID 20270166, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1-(1-naphthyloxy)-8-(N,N-dimethylamino)octane acetate (1.0 g) is dissolved in 50 ml water containing a stoichiometric equivalent of sulfuric acid, and the solution evaporated to dryness. The product is suspended in ethanol and filtered, air dried and recrystallized from methanol/acetone to yield 1-(1-naphthyloxy)-8-(N,N-dimethylamino)octane bisulfate.

Workup

  1. customthe solution evaporated to dryness
  2. filtrationfiltered
  3. customair dried
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-a8b9da8ff6b94919870caae5c47f6291
Source dataset
uspto-grants-1985_08
Patent number
US04536503

Reaction notes

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