Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → HCID 20270182, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Bromopyridine | HCID 12286 | — |
| 반응물 | Ethyl 3-(1h-indol-3-yl)propanoate | HCID 225390 | — |
| 촉매 | Copper oxide | HCID 14829 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | HCID 20270182 | HCID 20270182 | — |
반응 단계
A solution of 8.0 g of ethyl 3-(3-indolyl)propionate and 6.3 g of 3-bromopyridine in 100 ml of pyridine is refluxed with 5.0 g of copper oxide and 10 g of anhydrous potassium carbonate for 48 hours. Evaporation and chromatography on 300 g of silica with 1:1 ethyl ether:hexane as eluant yields 3-[2-(ethoxycarbonyl)ethyl]-N-(3-pyridyl)indole as an oil; Rf =0.2, IR (CH2Cl2) 1725 cm-1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04536505 |
| 출처 데이터셋 | uspto-grants-1985_08 |
| ORD ID | ord-ef2b67ec5c26474ea1dbd0ebc1a9451d |
| 출처 메모 | uspto-grants-1985_08 |