HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 20270210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | Ethyl indole-2-carboxylate | HCID 73125 | — |
| Catalyst | Copper oxide | HCID 14829 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 20270210 | HCID 20270210 | — |
Reaction Steps
A solution of 10.0 g of 2-carboethoxyindole and 5 ml of 3-bromopyridine in 50 ml of pyridine is refluxed with 5.0 g of copper oxide and 5.0 g of potassium carbonate for 72 hours. Filtration and evaporation yields an oil which is chromatographed on 110 g of silica with 15% ethyl acetate in toluene to yield 2-carboethoxy-N-(3-pyridyl)indole as an oil; IR (CH2Cl2) 1705 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04536505 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-0d4fca573f7f45d1812317aa5dea166c |
| Source note | uspto-grants-1985_08 |