HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20270209, compound → HCID 13490360, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20270209 | HCID 20270209 | — |
| Catalyst | HCID 178418647 | HCID 178418647 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13490360 | HCID 13490360 | — |
Reaction Steps
A solution of 3.3 g of 2-hydroxymethyl-N-(3-pyridyl)indole in 33 ml of dry toluene under nitrogen is refluxed with 16.5 g of silver carbonate for 24 hours. Filtration through celite and evaporation yields an oil which is purified by preparative layer chromatography on silica with methylene chloride-ethyl acetate (8:2) as the eluent to yield N-(3-pyridyl)indole-2-carboxaldehyde, m.p. 101°-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04536505 |
| Source dataset | uspto-grants-1985_08 |
| ORD ID | ord-5e63a9a291d4429096df2fa08742a8fe |
| Source note | uspto-grants-1985_08 |